Lydia Lynch, PhD
Lydia Lynch received her B.Sc. degree in Cell Biology and Genetics from University College Dublin, Ireland. She received her PhD in Immunology in 2008 from University College Dublin, in the lab of Prof. Cliona O’Farrelly in St. Vincent’s University Hospital.
Lydia received a Newman Fellowship for her early post-doctoral studies with Prof. Donal O’Shea in St. Vincent’s University Hospital, Dublin. Here they established the Immunology and Obesity Lab, which coordinates international, collaborative, translational research in obesity and its complications. Lydia then received the prestigious UNESCO-L’Oreal International Women In Science Fellowship, where she moved to Harvard Medical School to study iNKT cells in adipose tissue in the lab of Mark Exley. In 2009, Lydia received an International Marie Curie Fellowship to continue her postdoctoral studies in immunometabolism, in the labs of Prof. Michael Brenner and Prof. Ulrich von Andrian in Harvard. In 2013, she became a junior faculty member at Brigham and Women’s Hospital and Harvard Medical School. In 2014, Lydia started her independent lab with a joint appointment between the Division of Endocrinology and the Division of Rheumatology, Allergy and Immunology, at Brigham and Women’s Hospital and Harvard Medical School.
Lydia’s lab is interested in the effects of obesity and diet on immune cell functions, particularly innate cells including iNKT cells, NK cells and T cells. The Lynch lab also studies the role of the immune system in the regulation of metabolism and body weight, particularly the local immune system in adipose tissue in mice and humans.
Xavier Michelet, PhD
In the Lynch lab, Xavier works on the role of NK cells in adipose tissue, and the effects of obesity on lysosome function and cytotoxicity in natural killer (NK) cells.